Amino Acid Deficits and Dysregulation in CKD

 Presentation Description/Summary:

This presentation focuses on the intricate relationship between amino acid deficits, dysmetabolism, and chronic kidney disease (CKD) in dogs and cats within the realm of veterinary medicine. Chronic kidney disease poses a significant challenge in companion animals, with metabolic disturbances such as deficits in essential amino acids playing a crucial role in disease progression and management. Through an exploration of recent literature and clinical studies, this presentation elucidates the pathophysiological mechanisms underlying amino acid dysregulation in CKD, examines alterations in amino acid profiles observed in veterinary patients, and discusses potential therapeutic interventions to mitigate the clinical manifestations of CKD in dogs and cats.

Learner

Objectives:

By the end of this presentation, participants will be able to:

1. Understand the importance of amino acids in maintaining metabolic homeostasis and overall health in dogs and cats.


2. Describe the alterations in amino acid profiles observed in dogs and cats with CKD and their implications for disease progression and clinical outcomes.


3. Identify the potential factors contributing to protein-energy wasting (PEW) and amino acid dysregulation in veterinary patients with CKD.


4. Evaluate the role of nutritional therapy, including dietary management and amino acid supplementation, in combating PEW and optimizing clinical outcomes in dogs and cats with CKD.


5. Discuss potential challenges and considerations associated with amino acid supplementation in veterinary patients with CKD, including the production of uremic toxins and the balance between providing essential nutrients and exacerbating metabolic disturbances.