Abstract: Background – Breed-related neurologic disease identification expands notably each year. Currently, no peer-reviewed repository exists for clinicians to succinctly compare clinical signs and pertinent information to support a presumptive clinical diagnosis. Objective - The goal of this project is to generate an open-access repository of breed-related neurologic diseases, including clinically relevant information to aid in the identification of these diseases in clinical practice. Methods - The American and United Kennel Club registered breed lists were utilized, supplemented with additional breeds known to have breed-related neurologic conditions. Disease names were collected from published texts describing canine neurologic disease. The following publicly available internet platforms were accessed: Pubmed, Web of Science, Google Scholar, and Google search platforms. The keywords searched included: breed and (neurologic disorder, nervous, disease) or (clinical signs) or (additional neurologic terms). Retrieved information was stored in Excel format categorized by breed and disease, with updated searches performed weekly. Original peer-reviewed manuscripts (written in English) were downloaded and reviewed. Data extracted included breed, number of animals affected, sex, age of onset of signs, clinical signs, and other pertinent clinical information. Results - Over 411 breeds were reviewed for peer-reviewed evidence of neurologic disease, with over 1500 scholarly citations subsequently identified and stored in an Excel-based system. Conclusions & Clinical Importance - An open access, contemporary, single-site, and easily searchable repository of canine neurologic disease will assist primary care clinicians and practicing neurologists with comparison of the immediate clinical presentation to historically reported information and subsequently aid clinical diagnosis.
