Background: Cervical Disc Arthroplasty (CDA) using Adamo Spinal Disc™ has been used as a surgical treatment in dogs affected by Disc Associated Wobbler Syndrome. Implant subsidence and loss of mobility overtime were the most frequent issues reported. The most likely cause is lack of osseointegration due to excessive micromotion at the implant-bone interface. Tetranite® is a novel synthetic-mineral-organic adhesive biomaterial designed specifically to adhere to metallic implants and cortical or cancellous bone and shows promise in augmenting implant stabilization during healing.
Hypothesis/
Objectives: Evaluate the immediate post-operative adhesive properties of Tetranite and its implication on CDA using the Adamo Spinal Disc.
Methods: The C6-C7 vertebral unit, from six canine cadaver cervical spines, were biomechanically tested in sub-threshold axial compression, torsion, flexion-extension, and lateral bending, which was then followed by axial pull-out of the implant. Testing was sequentially performed in untreated spine (native group), treated spines with CDA without Tetranite (control group), and then treated spines with CDA with Tetranite (treatment group).
Results: ANOVA tests indicated that the treatment group was significantly less compliant (more stable) in comparison to the native group under flexion-extension and lateral bending, whereas the control group was not so.
Conclusions: Tetranite significantly improved immediate post-operative stability between the Adamo Spinal Disc and the vertebral endplate. The elimination of micro-motion at the implant-bone interface may facilitate osseointegration, which in turn may prevent subsidence and loss of mobility over time.
Learning Objectives:
Update on Cervical Disc Athroplasty for the treatment of Disc Associated Wobbler Syndrome in dogs
Update on new bone/implant adhesive technology
Update on Disc Associated Wobbler Syndrome surgical treatment