Asst Professor of Neurology University of Illinois Urbana Champaign Carle Illinois College of Medicine Urbana, Illinois, United States
Disclosure(s):
Graham R. Huesmann, MD/PhD: No financial relationships to disclose
THIS PRESENTATION WILL BE GIVEN VIA LIVE ZOOM Magnetic Resonance Elastography (MRE) utilizes a 60Hz low amplitude vibration applied to the brain with the image capture correlated with the sin wave of the stimulation in the scanner. Soft tissue will move a bit more than stiff tissue. This gives us a stiffness map of the brain as well as density. These physical characteristicts of the tissue are never before available aspects of brain tissue, a deep plapation. Our preliminary data on graduate students (everyones favorte test subject) shows a high correlation between memory performance and hippocampal stiffness. It also suggested a menarchial periodic change in both memory function and hippocampal stiffness in the famle cycling graduate students. Finally we found changes in the hippocampi of mesial temporal sclerosis patients that were unexpected, the unaffected side (non-epileptogenic) was very soft compared to age matched controls, so softening may be the early changes in epilepsy progression that normal MRI can not capture.
Learning Objectives:
Upon completion, participant will be able to understand the type of new information captured with magnetic resonance elastography
Upon completion, participant will be able to appreciate how MRE has led to a new understanding of hippocampal physiology and temporal lobe epilepsy
Upon completion, participant will be able to see the broad possible applications for this new technique
