Asst Professor of Neurology University of Illinois Urbana Champaign Carle Illinois College of Medicine Urbana, Illinois, United States
Disclosure(s):
Graham R. Huesmann, MD/PhD: No financial relationships to disclose
THIS PRESENTATION WILL BE GIVEN VIA LIVE ZOOM This talk will focus on the two of our new MRI sequences under development; SPICE and J-Resolve SPICE. SPICE utilizes MRI spectroscopy but significantly improves this, moving from a single 2Cm voxel to 0.5cm voxels, every voxel on a slice and all slices. This give a biochemical profile of the whole brain and not just one lesion or corresponding area. The J-resolve technique takes this a bit finer and allows us to visualize Glutamate and Gaba neurotransmitters. We have preliminary data on post-traumatic epilepsy and Mesial temporal sclerosis epilepsy that show high glutamate and low gaba in areas of seizure onset, thus confirming a long standing hypotesis about seizure cause. The potential for both these techniques is great.
Learning Objectives:
Upon completion, participant will be able to understand the type of new information captured with these new MRI sequences
Upon completion, participant will be able to appreciate how Spice and J-resolve Spice have led to a new understanding of hippocampal physiology and post-traumatic epilepsy
Upon completion, participant will be able to see the broad possible applications for this new technique
