Katie Sheats, DVM, PhD, DACVIM (LAIM), FHEA: No financial relationships to disclose
Presentation Description / Summary: Climate change has brought increasing frequency and severity of wildfires. Wildfire smoke leads to increased particulate matter (PM) exposure in horses and humans. In humans, the adverse respiratory impacts of wildfire smoke PM-exposure are well documented. Several recent studies have also described negative impacts of wildfire smoke on horse respiratory health. In this study, we analyzed paired BAL samples collected from otherwise healthy, adult horses, during acute natural exposure to wildfire smoke in the southeastern United States and during non-exposure conditions. This report will describe our “-omics” findings and compare the effects of natural wildfire smoke exposure on equine lower airways vs. other species.
Learner Outcomes: After attending this session, learners will be better able to:
Describe known impacts of wildfire smoke PM on equine and human respiratory health.
Relay findings from our study regarding effects of short term wildfire smoke exposure on equine BAL cell trascriptome, and BAL supernatant proteomics and lipidomics.
Describe knowledge gaps and future research needs to address treatments and mitigation efforts to maintain respiratory health in the face of increasing wildfire smoke PM-exposures.
Learning Objectives:
1. Describe known impacts of wildfire smoke PM on equine and human respiratory health.
2. Relay findings from our study regarding effects of short term wildfire smoke exposure on equine BAL cell trascriptome, and BAL supernatant proteomics and lipidomics.
3. Describe knowledge gaps and future research needs to address treatments and mitigation efforts to maintain respiratory health in the face of increasing wildfire smoke PM-exposures.
